All researchers, clinicians, and industry representatives interested in PC (and other rare skin conditions with PPK) are warmly invited by Professors Edel O’Toole and Eli Sprecher to join us for another special meeting of collaboration at:
The 17th Annual International Pachyonychia Congenita Consortium (IPCC) Symposium
Monday and Tuesday, June 28-29, 2021
8am-11am MDT Each Day
(10am-1pm EDT, 3pm-6pm UK, 4pm-7pm France, 5pm-8pm Israel Each Day)
to be held virtually
Please register and join us for presentations and discussions by those who are doing both clinical and translational research for PC and other PPKs. Also, if you know of others in your clinics and labs, or even students who may be interested in learning more about these rare skin diseases, please feel free to invite them to register and enjoy participating with some of the key leaders in our field.
We are excited to resume our yearly gathering of exceptional professionals who share concern regarding patients who deal with pain each day of their lives. Because despite the name Pachyonychia Congenita, PC is much more than thick nails!
Please contact us at info@pachyonychia.org with questions.
Click here for the 2021 IPCC Schedule Only
Click here for the 2021 IPCC Full Program Book
2021 IPCC Presenters
 | Diana Blaydon, PhD Lecturer, Blizard Institute, Queen Mary University of London
Spatial transcriptomics of iRhom2 mouse model paw skin. |
 | Lynn M. Boyden, PhD Yale University School of Medicine, Department of Genetics
ASPRV1 mutations in dominant lamellar ichthyosis |
  | Christopher G. Bunick, MD, PhD Assistant Professor of Dermatology, Yale University
Joyce Teng, MD, PhD Structural modeling guided understanding of genotype- phenotype correlation in PC |
 | John Connelly, PhD Reader in Bioengineering, Centre for Cell Biology and Cutaneous Research, Queen Mary University of London
Biomechanical analysis of the keratin cytoskeleton and its role in cellular mechano-sensing |
 | Pierre A. Coulombe, PhD G. Carl Huber Professor and Chair Department of Cell & Developmental Biology University of Michigan Medical School
A rationale for the interplay between expression and function for intermediate filament proteins |
 | Kathleen J. Green, PhD Joseph L. Mayberry Professor of Pathology and Professor of Dermatology Northwestern University Feinberg School of Medicine
How desmosomes help drive tissue form and function |
 | Alain Hovnanian, MD, PhD INSERM UMR 1163, Laboratory of genetic skin diseases, Imagine Institute, Necker hospital for sick children, Paris University, Paris, France
A new case series of Olmsted syndrome subjects confirms EGFR activation and that targeted systemic EGFR inhibition shows remarkable efficiency and acceptable side effects |
 | Roger L. Kaspar, PhD CSO and founder, Ayni Therapeutics
Are fully-modified therapeutic siRNAs the answer for PC? |
  | Wes Kaupinen Founder and CEO, Palvella Therapeutics
Braham Shroot, PhD Palvella Therapeutics: PC clinical studies |
 | David Kelsell, PhD Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London
Mouse PPK models; bulk and spatial RNAseq |
 | Akiharu Kubo, MD, PhD Keio University School of Medicine
Phenotypic and pathogenetic heterogeneity in desmoglein 1 deficiencies |
 | Sonja Lehmann PhD Student, RWTH Aachen University, Institute of Molecular and Cellular Anatomy
Mitochondria and lysosomes in pachyonychia congenita pathogenesis |
 | Thomas Magin, PhD Professor of Cell and Developmental Biology, University of Leipzig
Toward a chemical compound-based therapy approach for EBS |
 |
Mor Pavlovsky, MD
Co-existence of pachyonychia congenita and hidradenitis suppurativa: more than a coincidence |
 | Liat Samuelov, MD Division of Dermatology, Tel-Aviv Medical Center
Revisiting pachyonychia congenita: a case control study in 815 patients |
 | Lloyd Steele, MBChB Academic Clinical Fellow, Barts Health NHS Trust
Prevalence and characterisation of itch in pachyonychia congenita |
  | Albert G. Wu New York Medical College | M.D. Candidate | Class of 2022 Co-President | National Dermatology Interest Group Association
Shari R. Lipner, MD Patient-reported quality of life differentials in pachyonychia congenita management |
