Awarded Grants

Awarded a one-year, $88,200 grant from Pachyonychia Congenita Project. The main problem of patients with PC is the intense pain they feel when walking. This is due to the malfunction of some skin-forming proteins, especially in the soles of the feet. This malfunction is due to errors (mutations) … [Read more...] about PCGA0001-2023

Awarded a one-year, $97,500 grant from Pachyonychia Congenita Project. Pachyonychia congenita (PC) is characterized by excessive callus formation which is caused by thickening of the outer layer of the skin, the epidermis. To form the epidermis, the resident cells have to undergo drastic changes … [Read more...] about PCGA0003-2023

Awarded a one-year, $100,000 grant from Pachyonychia Congenita Project. The project aims at improving the understanding of the disease mechanisms involved in painful plantar keratoderma in PC patients. It will compare the expression of genes and proteins involved at a global and cellular level. … [Read more...] about PCGA0004-2023

Awarded a two-year, £144,581 grant from Pachyonychia Congenita Project. Several genetic skin conditions specifically affect the skin found on our palms and soles (palmoplantar), including the palmoplantar keratodermas (PPKs). PPKs are characterised by a thickening of palmoplantar skin, which is … [Read more...] about PCGA0001-2022