• Skip to main content
  • Skip to footer

Pachyonychia Congenitia Project

Fighting for a cure. Connecting & helping patients. Empowering Research.

Donate
VIEW MENUMENU
  • Pachyonychia Congenita
        • What Is Pachyonychia Congenita?
          • Could I Have PC?
          • Getting Diagnosed
          • Genetics
          • Image Library
          • Glossary
          • Brochures
        • Patient Registry (IPCRR)
          • Patient Registry Data
        • Understanding my Genetic Testing Results
          • PC-K6a
          • PC-K6b
          • PC-K6c
          • PC-K16
          • PC-K17
          • Other Conditions With Painful Palmoplantar Keratoderma
        • Managing and Caring For PC
          • Tips and Tools
          • Living With PC
          • PC & Children
          • Working With Medical Professionals
          • Family & Friends: How To Help
          • Video Library
  • For Professionals
        • For Professionals
          • International PC Consortium
          • Pharmaceutical Partners
          • Refer a Patient
          • Patient Registry (IPCRR)
            • Patient Registry Data
            • Other Conditions With Painful Palmoplantar Keratoderma
          • Advocacy Partners
        • PC Research
          • Apply for a Grant
          • Published Research Articles
          • Clinical Trials
        • Patient Voices
          • Quality of Life
          • Patient Stories
          • Patient-Focused Drug Development Meeting
  • Ways To Give
        • Ways You Can Give
          • Donate
          • Donate Just Giving UK
          • PC Love Builders
          • Legacy Society (Planned Giving)
          • Combined Federal Campaign
          • Giving Stock
        • Raise Awareness
          • How You Can Help
          • Fundraising Ideas
          • Share Your Story
          • PC Advocates
          • Volunteer
  • News & Events
        • News
          • Current Newsletter
          • Newsletter Archives
          • Sign up for our Newsletter
        • Events
          • Patient Support Meetings
          • IPCC Meetings
          • Video Library
  • About Us
        • About PC Project
        • Medical and Scientific Advisory Board
        • Financial & Legal Information
        • Contact Us

UK Study to Evaluate the Safety & Effectiveness of KM001, a potential treatment for PC

February 21, 2023 by Pachyonychia

Kamari Pharma is happy to announce the initiation of a new study in the UK to evaluate the safety and efficacy of KM001-a new potential treatment for PC and PPPK1 patients.

KM001 is a novel, small molecule which acts as TRPV3 inhibitor- a protein that plays essential role in keratoderma and itch development and formulated into a topical cream.

The KM001 cream is already testing in a phase 1b study in Israel, enrolling PC and PPPK1 patients and recently a new study was initiated at Prof Edel O’Toole’s site in the Royal London Hospital. The study is a proof-of-concept study and will enroll up to 10 patients, for a treatment period of 12 weeks.

Kamari Pharma hopes that the results of these studies will be able to support further development of the KM001 topical cream, which may provide a new solution for patients with PC and PPPK1.

For more information visit ClinicalTrials.gov study: NCT05956314

Filed Under: Clinical Trials, News

Footer

PC Project logo in white
PACHYONYCHIA CONGENITA PROJECT

P.O. Box 17850
Holladay, UT 84117

info@pachyonychia.org

801-987-8758

  • Facebook
  • Instagram
  • LinkedIn
  • Twitter
  • YouTube

Sign up for our Newsletter

Loading

Support PC Project

There are many ways you can help improve the lives of those who suffer from Pachyonychia Congenita.

Learn More
  • Contact Us
  • About Us
  • Donate
  • Patient Registry

Copyright © 2023 PC Project. All rights reserved. Pachyonychia Congenita Project is a 501(c)(3) under federal tax guidelines. Using this site means you accept its terms as outlined in the disclaimer and privacy policy.